Bournemouth vs Manchester United: Mourinho makes seven changes, drops Alexis, Lukaku
United lost 1-0 to West Brom at Old Trafford on Sunday, ensuring that Manchester City were crowned champions.
Goalkeeper David De Gea, Chris Smalling, Ander Herrera and Paul Pogba are the only ones to keep their places.
De Gea has been named captain for the match.
Matteo Darmian has been recalled for his first Premier League start since October, while Phil Jones is back after missing more than two months through injury.
Luke Shaw, Marouane Fellaini, Jesse Lingard, Anthony Martial and Marcus Rashford also return to the team.